Betekenis van:
aneuploidy

aneuploidy
Zelfstandig naamwoord
    • an abnormality involving a chromosome number that is not an exact multiple of the haploid number (one chromosome set is incomplete)

    Hyperoniemen


    Voorbeeldzinnen

    1. Benomyl in particular, but also thiophanate-methyl, is metabolised to carbendazim and all three substances produce numerical chromosomal aberrations (aneuploidy) in mammalian cells, exposed in vivo.
    2. The mechanism of aneuploidy induction is well understood and consists of inhibition of polymerisation of tubulin, the protein that is essential for the segregation of chromosomes during cell division: it does not involve any interaction with DNA.
    3. positive results from tests showing mutagenic effects in the germ cells of humans, without demonstration of transmission to progeny; for example, an increase in the frequency of aneuploidy in sperm cells of exposed people.