Betekenis van:
phosphatase
phosphatase
Zelfstandig naamwoord
- any of a group of enzymes that act as a catalyst in the hydrolysis of organic phosphates
Hyperoniemen
Voorbeeldzinnen
- Phosphatase
- Phosphatase activity
- Phosphatase test
- DETERMINATION OF ALKALINE PHOSPHATASE ACTIVITY
- Alkaline phosphatase substrate solution, pH 9,8
- sufficient to ensure a negative reaction to a phosphatase test,
- A unit of alkaline phosphatase activity is the amount of alkaline phosphatase enzyme that catalyses the transformation of 1 micromole of substrate per minute.
- Prepare the appropriate dilution of secondary antibody-alkaline phosphatase conjugate in blocking buffer.
- Prepare an appropriate dilution of anti-mouse immunoglobulins conjugated with alkaline phosphatase in PBS.
- The alkaline phosphatase activity is expressed as milliunits of enzyme activity per litre (mU/l).
- When determining alkaline phosphatase activity, ISO standard 11816-1 must be applied as reference method.
- Add 100 µl alkaline phosphatase substrate solution (Appendix 4) to each well.
- after having undergone heat treatment such as to show a negative reaction to the phosphatase test;
- Dissolve 2 phosphatase substrate 5 mg tablets (Sigma) per 15 ml of solution.
- after having undergone heat treatment such as to show a negative reaction to the alkaline phosphatase test; and